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γ-Aminobutyric acid (gamma-aminobutyric acid) , or GABA , is the chief inhibitory neurotransmitter in the developmentally mature mammalian central nervous system. Its principal role is reducing neuronal excitability throughout the nervous system.
GABA is sold as a dietary supplement in many countries. It has been traditionally thought that exogenous GABA (i.e. taken as a supplement) does not cross the blood–brain barrier, but data obtained from more recent research describes the notion as being unclear.
The carboxylate form of GABA is γ-aminobutyrate.